3-(Naphthalen- 1 -yl) benzo [ d ]isothiazole 1 , 1-dioxide (1g): Yellow solid Mp = 168–169 o C 1 H NMR (600 MHz, CDCl 3 ): ? 8.20 ( d , J = 7.8 Hz, 1H), 8.11 ( d , J = 7.8, SAGECHEM LIMITED: Country: China 5Fl. 501Room, Tower A, New Youth Plaza, NO.8 Jia Shan Road, Hangzhou, China 310006, Aryl-substituted benzo [ d ] isothiazol-3 -ylamine analogues are provided, of the Formula (I): wherein variables are as described herein. Such compounds are ligands that may be used to modulate capsaicin in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological capsaicin receptor activation in humans, domesticated companion animals and livestock …
cas?????????????????c7 h5 n1 s2?cas?????????????????,?????c7 h5 n1 s2?????????????????????????, 1 -Benzoyl-2-phenylacetylene reacted with N-(carbamimidoyl)thiourea in glacial acetic acid saturated with 20% HBr to give (4,6-diphenyl- 2H – 1 ,3-thazin-2-ylidene)guanidine hydrobromide.
